SELECTED PUBLICATIONS

Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor
Rodrigues T; Werner M; Roth J; da Cruz EHG; Marques MC; Akkapeddi P; Lobo SA; Koeberle A; Corzana F; da Silva Júnior EN; Werz O; Bernardes GJL*

Chem. Sci. 2018, 6885–7018.

88b-01
88b-01

Chemo and regioselective lysine modification on native proteins
Matos MJ; Oliveira BL; Martínez-Sáez N; Guerreiro A; Cal PMSD; Bertoldo J; Maneiro M; Perkins E; Howard J; Deery MJ; Chalker JM; Corzana F; Jiménez-Osés G; Bernardes GJL*

J. Am. Chem. Soc. 2018140, 4004–4017.

TOC
TOC

Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents
Bernardim B; Cal PMSD; Matos MJ; Oliveira BL; Martínez-Sáez N; Albuquerque IS; Corzana F; Burtoloso ACB;
Jiménez-Osés G; Bernardes GJL*

Nat. Commun. 2016, 7, 13128

homepage3-03
homepage3-03

Oxetane grafts installed site-selectively on native disulfides to enhance protein stability and activity in vivo
Martínez-Sáez N; Sun S; Oldrini D; Sormanni P; Boutureira O; Carboni F; Compañón I; Deery MJ; Vendruscolo M; Corzana F; Adamo R; Bernardes GJL*

Angew. Chem. Int. Ed. 201747, 14963–14967

anie201708847-toc-0001-m
anie201708847-toc-0001-m

Spontaneous CO release from RuII(CO)2-protein complexes in aqueous solution, cells and mice
Ferreira MC; Albuquerque IS; Matak-Vinkovic D; Coelho AC; Carvalho SM; Saraiva LM; Romão CC; Bernardes GJL*

Angew. Chem. Int. Ed. 2015, 54, 1172–1175

TOC_ACIE
TOC_ACIE