REVIEWS

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The impact of activity-based protein profiling in malaria drug discovery
Carvalho LAR*; Bernardes GJL*
ChemMedChem 2022, 17, e202200174

malaria review image

Transition metal mediated bioorthogonal release
Sabatino V; Unnikrishnan VB; Bernardes GJL*
Chem Catal., 2022, 2, 39–51

 

transition review image
The role of reversible and irreversible covalent chemistry in targeted protein degradation
Kiely-Collins H; Winter GE; Bernardes GJL*
Cell Chem. Biol. 2021, 28, 952–968
covalent review image

Mechanistic insights into transition metal-mediated bioorthogonal uncaging reactions
Latocheski E; Dal Forno GM; Ferreira TM; Oliveira BL; Bernardes GJL; Domingos JB
Chem. Soc. Rev. 2020, 49, 7710–7729

uncaging review image

Biomimetic peptide self-assembly for functional materials
Levin A; Hakala T; Schnaider L; Bernardes GJL; Gazit E; Knowles TPJ
Nat. Rev. Chem. 2020, 4, 615–634

biomimetic peptide review image

Machine learning for target discovery in drug development
Rodrigues T; Bernardes GJL*
Curr. Opin. Chem. Biol. 2020, 56, 16–22

machine learning review image

Contemporary approaches to site-selective protein modification
Hoyt EA; Cal PMSD; Oliveira BL; Bernardes GJL*
Nat. Rev. Chem. 2019,3, 147–171

contemporary review image

Computational advances in combating colloidal aggregation in drug discovery
Reker D; Bernardes GJL; Rodrigues T
Nat. Chem. 2019, 11, 402–418

computational review image

Inverse electron demand Diels–Alder reactions in chemical biology
Oliveira BL; Guo Z; Bernardes GJL*
Chem. Soc. Rev2017, 46, 4895–4950

IEDDA review image

Trends in therapeutic drug conjugates for bacterial diseases: a patent review
Cal PMSD; Matos MJ; Bernardes GJL*
Expert Opin. Ther. Pat. 2016, 27, 179–189

Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents
Rodrigues T; Sieglitz F; Bernardes GJL*
Chem. Soc. Rev. 2016, 45, 6130–6137

Construction of homogeneous antibody-drug conjugates using site-selective protein chemistry
Akkapeddi P; Azizi S-A; Freedy A; Cal PMSD; Gois PMP; Bernardes GJL*
Chem. Sci. 2016, 7, 2954–2963

Advances in chemical protein modification
Boutureira O; Bernardes GJL*
Chem. Rev. 2015, 115, 2174–2195

Protein micro and nano capsules for biomedical applications
Shimanovich U; Bernardes GJL*, Knowles TJ; Cavaco-Paulo A
Chem. Soc. Rev. 2014, 43, 1361–1371

Developing drug molecules for therapy with carbon monoxide
Romão CC; Seixas JD; Blättler WA; Bernardes GJL*
Chem. Soc. Rev. 2012, 41, 3571–3583

Towards improved therapeutic CORMs: Understanting the reactivity of CORM-3 with proteins
Santos-Silva T; Mukhopadkyay A; Seixas JD; Bernardes GJL; Romão CR; Romão MJ
Curr. Med. Chem. 2011, 18, 3361–3366

Combined approaches to the synthesis and study of glycoproteins
Bernardes GJL; Castagner B; Seeberger PH
ACS Chem. Biol. 2009, 4, 703–713

A “tag-and-modify” approach to site-selective protein modification
Chalker JM; Bernardes GJL; Davis BG
Acc. Chem. Res. 2011, 44, 730–741

Chemical modification of proteins at cysteine: Opportunities in chemistry and biology
Chalker JM; Bernardes GJL; Lin AY; Davis BG
Chem. Asian J. 2009, 4, 630–640