Dr Srinivasa Rao Adusumalli
Marie Sklodowska-Curie Postdoctoral Researcher
I am currently a Marie Curie Postdoctoral Fellow in the GBernardes group in Cambridge. I work on developing new chemical methods for redesigning the structure and function of biomolecules. Also, I am developing new reversible covalent small molecules to enable the degradation of target proteins in the context of acute myeloid leukemia (AML).
Before joining the group, I worked at Plabeltech Private Limited, India and was involved in developing the toolbox for precision labeling of proteins/antibodies. During my Ph.D. under the supervision of Dr Vishal Rai at the Indian Institute of Science Education and Research (IISER Bhopal, India), I developed modular methods for single-site labeling of native proteins. I obtained my M.Sc. in Organic Chemistry (2009) from Acharya Nagarjuna University, India.
Areas of expertise:
Organic chemistry, protein modification, antibody-drug conjugates and chemical biology.
2. Serine-Selective Bioconjugation
Vantourout JC; Adusumalli SR; Knouse KW; Flood D; Ramirez A; Padial NM; Istrate A; Maziarz K; deGruyter JN; Merchant RR; Qiao JX; Schmidt MA; Deery MJ; Eastgate MD*; Dawson PE*; Bernardes GJL*; Baran PS*
J. Am. Chem. Soc. 2020, 142, 17236−17242