Dr Valerio Sabatino
SNSF Postdoc.Mobility Fellowship
I joined the GBernardes group in Cambridge in March 2021. I am looking into innovative applications to advance biomedical research. My research work involves the design, synthesis and application of chemical technologies for drug discovery. I am active in the fields of targeted protein degradation, antibody-drug conjugates and controlled drug release.
I received a MSc degree in Medicinal Chemistry and Pharmaceutical Technologies from the University of Calabria, Italy, in 2012 and a MRes degree in Drug Discovery and Development from Imperial College London, UK, in 2014.
After an industrial internship at the Novartis Institute for Biomedical Research, Switzerland, in 2015, I started doctoral studies in the group of Prof. Thomas Ward at the University of Basel, Switzerland. My PhD work focused on artificial metalloenzymes and bioorthogonal catalysis, particularly on the applications of aqueous olefin metathesis in chemical biology and drug discovery.
Areas of expertise:
Organometallic chemistry, bioinorganic chemistry, bioorthoogonal catalysis and protein chemistry
1. Controlled in-cell generation of active palladium(0) species for bioorthogonal decaging
Konč J; Sabatino V; Jiménez-Moreno E; Latocheski E; Rodríguez Pérez L; Day J; Domingos JB; Bernardes GJL*
Angew. Chem. Int. Ed. 2022, e202113519
2. Transition metal mediated bioorthogonal release
Sabatino V; Unnikrishnan VB; Bernardes GJL*
Chem Catal., 2022, 2, 39–51